
Overview of the Sustainable Off-Grid Solutions for Pharmacies and Hospitals in Africa (SophiA) Project
Despite ongoing urbanization across Africa, the majority of the population still resides in rural and remote areas, where infrastructure development remains limited. These regions face significant challenges such as lack of access to healthcare, education, clean water, and reliable electricity, contributing to higher rates of illness and poverty compared to urban centres. According to reports, Sub-Saharan Africa has approximately 120,000 public health facilities (22,000 hospitals and 98,000 health posts), of which around 26% lack any electricity access, and only 28% have reliable power supply.

Access to good healthcare is critical for sustainable development. However, many rural medical centres operate under harsh conditions – using polluted water, lacking cooling for medicines, and facing poor sanitation – largely due to unreliable electricity and water supply. Although half of the population in Sub-Saharan Africa lacks electricity, the region has abundant renewable energy potential that can be effectively harnessed through off-grid solar photovoltaic (PV) systems.

To address the above-mentioned challenges facing the African Continent, Makerere University in partnership with 13 organizations across Europe and Africa developed a project titled, “Sustainable Off-grid solutions for Pharmacies and Hospitals in Africa (SophiA)”. The five-year project that began on 1st October 2021 is funded by the European Union (Project: 101036836 – SophiA – H2020-LC-GD-2-3-2020). At Makerere University, the project is coordinated by Dr. Nicholas Kiggundu, Associate Professor in the Department of Agricultural and Biosystems Engineering, College of Agricultural and Environmental Sciences (CAES).

Piloted in Burkina Faso, Cameroon, Malawi, and Uganda, SophiA aims to provide sustainable off-grid energy solutions to rural and remote health facilities, fostering economic growth and ensuring equitable access to energy and healthcare. Using various technologies, such as photovoltaics, solar thermal, electrical and thermal storage, water treatment and natural refrigerants with low global warming potential, SophiA has developed and manufactured locally innovative, modular, affordable and efficient solar powered systems for providing:
- Safe and clean drinking water, free of bacteria and viruses, and deionised water for medical purposes;
- Hot water and steam production for thermal requirements of the hospitals;
- Cooling of medicines and food at +5°C;
- Low temperature storage of blood plasma and vaccines at -30°C;
- Ultra-low temperature storage of sensitive medication (e.g. some Covid-19 or Ebola vaccines) at -70°C.

In addition, PV MedPort, a simple and 100% solar-powered solution has been developed and tested as a mobile health care station in small remote areas in 4 different geographical conditions in Africa. The SophiA system has been manufactured in Africa and will provide, for the first-time, innovative solutions based on climate-friendly natural refrigerants to cover cooling demand for three different temperature ranges (-70°C, -30°C and +5°C). The system has been tested and demonstrated at four rural hospitals in remote regions throughout the African continent covering the major geographical regions and different climatic conditions in Burkina Faso, Cameroon, Malawi and Uganda.

SophiA Project initiatives in Uganda
In Uganda, all Health Centre IV hospitals with surgical theatres have been connected to the national grid except Buvuma Health Centre IV, which serves over 120,000 people scattered across 52 islands. Recognizing this gap, the Ministry of Health selected Buvuma Health Centre IV for the SophiA project to demonstrate sustainable off-grid solutions.

The SophiA System at Buvuma Health Centre IV provides the following services:
- Off-grid electricity supply
- Safe, clean drinking water for patients, staff, and the community
- Hot water and steam systems crucial for maternal care
- Solar-powered cooking and meal preparation
- Cooling systems for surgery and intensive care units
- Refrigeration for medicines at +5°C, blood plasma storage at -30°C, and ultra-low temperature storage (-70°C) for sensitive vaccines such as those for COVID-19 and Ebola

Training of Trainers Workshop
As the SophiA project approaches completion in September 2025, it is vital to establish a skilled pool of technicians capable of handling maintenance and minor repairs of the system components, including solar panels, water treatment units, generators, batteries, and cooking kits.
From June 23 to 27, 2025, Makerere University hosted a comprehensive Training of Trainers workshop. The training programme encompassed a diverse range of topics delivered by subject matter experts from institutions, including Makerere University (Department of Agricultural and Biosystems Engineering – CAES, and the College of Engineering, Design, Art and Technology – CEDAT), Hochschule University of Applied Sciences, and Busitema University. Participants were carefully selected from diverse professional backgrounds, including recent engineering graduates from CAES and CEDAT, Makerere University, University technical staff, personnel from Kyambogo University, officials from Buvuma District Works and Health Departments, and electricians from Kampala City. The training sessions were conducted at Makerere University and Buvuma Health Centre IV Hospital.

Training Modules Included:
- Sustainable energy systems and their practical applications
- Energy generation and storage technologies
- Solar water heating: design, operation, maintenance, and performance optimization of solar water heaters, crop dryers, and concentrating solar heaters
- Solar PV technologies in Uganda: cell technology, system design, operations, maintenance, and hands-on practicals for standalone and grid-connected systems
- Public health implications of water quality
- Water treatment and quality management, including protocols, parameters, and case study on the MCDI treatment system
- Water quality testing methodologies
- Introduction to sustainable refrigeration and cooling technologies
- Environmental impact and safety considerations for refrigerants
- Refrigeration cycles and component overview
- Life cycle assessment of SophiA technologies
- Thermal energy storage within the SophiA system
- Steam as a productive energy source

The Training Sessions
Day One: Introduction to foundational concepts in solar energy technologies
The first day of the SophiA Train the Trainers Workshop focused on building foundational knowledge in sustainable and solar energy systems. Led by Dr. Peter Tumutegyereize and Dr. Francis Mujjuni, participants explored a range of technologies and applications critical to clean energy deployment.

Key topics included:
Sustainable Energy Systems: Introduction to renewable energy systems including bioenergy, hydro, wind, geothermal, hydrogen fuel cells, and battery storage.
Solar Radiation & Geometry: Understanding solar constants, irradiance, and the impact of atmospheric conditions on solar performance.
Solar Thermal Technologies: Detailed look at solar water heating systems (FPCs and ETCs), maintenance, sizing, and solar dryers for agricultural and industrial use.
Photovoltaic (PV) Systems: Working principles, types of PV cells, performance factors, and diagnostics. Practical testing techniques and metrics like Voc, Isc, MPP, and PR were discussed.
Simulation & Application: Olivia Nakiwanuka demonstrated a PVsyst-based simulation of a 2.55 kWp standalone system for a conference hall, showing a high solar fraction (97.88%) and low LCOE (USD 0.03/kWh).
The sessions emphasized practical skills, performance analysis, and real-world application, equipping participants to train others and support solar adoption, especially in rural and off-grid settings.
Day Two: Water Treatment Technologies
The second day focused on water treatment technologies relevant to low-resource healthcare settings. Facilitated by Sneha De and Mr. Duc Dinh Ngoc from Hochschule Karlsruhe University, sessions covered technical, environmental, and operational challenges, with contributions from Dr. Joshua Wanyama on water quality management and Dr. Prossie Nakawuka on practical water testing.
Key challenges addressed included unreliable water supply and contamination in healthcare facilities, emphasizing the need for decentralized water treatment, especially in rural areas.
Sneha De reviewed biological and physical/chemical water treatment methods, highlighting technologies such as activated sludge, filtration, membrane bioreactors, and advanced disinfection techniques. The SophiA modular water treatment system, integrating ultrafiltration and membrane capacitive deionisation (MCDI), was introduced as a scalable solution for producing safe drinking and deionised water for medical use.

Mr. Duc Dinh Ngoc trained participants on the MCDI technology, an energy-efficient method for salt and fluoride removal suitable for low-salinity water.
Dr. Joshua Wanyama discussed the water quality management protocols, outlining key physical, chemical, and biological water parameters and monitoring strategies, including modern IoT-based tools, to ensure water safety and public health.
The day concluded with a hands-on lab session by Dr. Prossie Nakawuka, where participants practiced water quality testing using turbidimeters, incubators, and filtration techniques.
Overall, Day Two combined theoretical insights, technology demonstrations, and practical skills, preparing participants to implement sustainable water treatment and quality management systems in healthcare environments.
Day Three: Refrigeration and Cold Storage
The third day of the SophiA workshop focused on sustainable refrigeration and cold storage technologies tailored for healthcare in Sub-Saharan Africa. Experts discussed energy-efficient, climate-friendly cooling solutions vital for vaccine storage, medicines, and diagnostics, especially in off-grid and rural settings.
Key highlights included the introduction of solar-powered and biomass-based refrigeration systems, thermal energy storage methods, and the use of natural refrigerants like propane, ammonia, and CO₂ as environmentally safer alternatives. Presentations emphasized the critical role of refrigeration in healthcare and the urgent need to replace harmful chemicals with sustainable technologies.
Sessions covered real-world applications such as the SophiA cooling containers in Burkina Faso, safety protocols for flammable refrigerants, and the environmental and economic benefits of solar refrigeration systems assessed through life cycle analysis.
The day ended with an interactive quiz and discussion, reinforcing learning and encouraging participants to apply sustainable cooling practices in their communities.
Day Four: World Refrigeration Day & Field Visit to Buvuma Island
The fourth day of the SophiA Train the Trainers workshop was dedicated to the celebration of the World Refrigeration Day and a field excursion to Buvuma Island, providing participants with a unique opportunity to witness the SophiA system in action. The day was coordinated by Dr. Sarah Bimbona and Dr. Nicholas Kiggundu, who led the delegation to Buvuma Health Centre IV, the pilot site for the SophiA installation in Uganda.

The visit served as both a practical extension of the previous day’s technical sessions and a community engagement event. Participants were able to observe the installed SophiA system, which integrates solar-powered refrigeration, water treatment and steam generation technologies designed for off-grid healthcare settings. During the visit, Dr. Kiggundu provided a detailed briefing to local stakeholders, including representatives from the Buvuma District Local Government, delegates from the Buganda Kingdom, and members of the local community. He explained how the SophiA system will enhance healthcare delivery on the island through reliable cold storage for vaccines and medicines, access to clean drinking water, and steam generated for cooking and use in the maternity wards.
As part of the long-term sustainability plan for the SophiA system, the launch of SophiA Water was announced, an entrepreneurial initiative designed to generate revenue locally for the operation and maintenance of the system.
The field trip ended with a certificate awarding ceremony in appreciation of the participants’ dedication and active engagement throughout the training programme.